CPSA Metabolomics 2017

Preliminary Program

Updated March 10, 2017

Sunday March 12  Pre-Conference Events

4:30 pm
Start & Meet:
UF Hilton & Conference Center

CPSA 5K

Kick off the week with the CPSA 5K (it's a walk in the park!) Join friends and colleagues for a leisurely walk, jog, or run through the beautiful UF campus and all for a good cause!

Sign up online - Free!

Organizers: Timothy Garrett, University of Florida; Nicole Matz, PRA Health Sciences; Michelle Reid, University of Florida; Martin Steel, McKinley Scientific; Shane Needham, Alturas Analytics

"Together We Can Go Farther"

Monday March 13  Pre-Conference Workshop & Events

9:00 am

NEW! CPSA Open Golf Event

Mark Bostick Golf Course on the UF Campus

Organizers: Paul Corcoran, McKinley Scientific and Steve Fannin, Bruker Daltonics

Sign up to join in on the fun!

1:00 pm - 4:00 pm
UF Clinical & Translational Science Institute

Workshop

Don Chace, Medolac Laboratories
Mike Lee, Milestone Development Services

Register for the workshop when you register for the meeting. There is no workshop registration fee for CPSA Metabolomics attendees.

5:00 pm - 7:00 pm

Welcome Reception & Metabolomics Lecture Series

Opening Remarks
Timothy Garrett, University of Florida and Mike Lee, Milestone Development Services

Welcome and Introduction
Suraj Dhungana, Waters Corporation

Applications of Metabolomics for Clinical and Translational Research
Amrita Cheema, Georgetown University

Tuesday March 14

7:30 am - 8:30 am
University Foyer

Registration & Coffee

8:30 AM - 8:45 AM

Welcome & Opening Remarks

Timothy Garrett


Timothy Garrett
University of Florida

Mike Lee


Mike S. Lee
Milestone Development Services

8:45 am - 9:30 am

Plenary Lecture

Irwin Kurland

Metabolic Phenotyping:
From Model Organisms to Man
Irwin Kurland
Einstein College of Medicine

9:45 am - 11:15 am

Biomarker Stability/Sample Integrity

Discussion Leader: Alla Kloss, Genzyme

One Chapter From a Manual on How to Ruin a Metabolomics Study
Alla Kloss, Sanofi

Biomarkers for Human Plasma Sample Quality using an IROA-Labeled Universal Internal Standard
Casey Chamberlain, University of Florida

Examining Heat Treatment for Stabilization of the Lipidome
Jeremy Koelmel, University of Florida

11:30 am - 1:30 pm

Lunch: Vendor Spotlight & Poster Review

Removing the Data Processing Bottleneck: Move Efficiently from Data to Structure to Pathway with New Thermo Scientific Compound Discoverer 2.0
Amanda Souza, Thermo Fisher Scientific

Profiling of Organic Acids in Mouse Muscle Using Ion Chromatography/Mass Spectrometry
Christopher Petucci, Sanford Burnham Presby Medical Discovery Institute

Using Proteometabolomics to Examine Mechanisms of Drug resistance in Multiple Myeloma
John Koomen, H. Lee Moffitt Cancer Center and Research Institute

Lunch served in lobby as you mix and mingle with our vendors and poster authors

1:45 pm - 3:00 pm

Personalized Metabolism

Discussion Leaders: Don Chace, Medolac Laboratories and Emily Ehrenfeld, New Objective

Using Proteometabolomics to Examine Mechanisms of Drug Resistance in Multiple Myeloma
John Koomen, H. Lee Moffitt Cancer Center and Research Institute

Translational Metabolomics in Biopharma
Michael Reily, Bristol-Myers Squibb

Metabolomics in the Clinic: Discriminating Between Research/Development and Application/Service
Don Chace, Medolac Laboratories

3:30 pm - 5:00 pm

Clinical Applications of Metabolomics and It's Role on Diagnosis and Therapeutic Response and Monitoring

Discussion Leader: Gustavo Maegawa, University of Florida

Use of Ion Chromatography/Mass Spectrometry for Targeted Metabolite Profiling of Polar Organic Acids
Chris Petucci, Sanford-Burnham Medical Research Institute

Biochemical Genetics the Triple Quad Way
Cheryl Lee Garganta, University of Florida

Routine Discovery Metabolomics Workflows on X500R QTOF System
Matthew Skaley, SCIEX

6:00 pm

Sponsored Social Event

Play Ball!
The Gators take on the Florida State Seminoles
McKethan Stadium
First pitch at 6:30pm

UF vs FS

Wednesday March 15

7:30 am - 8:30 am

Registration & Coffee

8:30 am - 10:00 am

Investigating Homeostatsis:
Technologies and Methodologies for Drug Discovery

Discussion Leader: John Janiszewski, Pfizer

Using metabolism to support drug discovery: from target identification to biomarker validation
David Pirman, Agios

Leveraging MIMOSA-based fluxomics to unravel the mechanism of action of lead matter in early drug discovery
Darren Dumlao, Pfizer

Fluxing around: Creating computational infrastructure for metabolic labeling experiments
Abhishek Jha, Elucidata

10:15 am - 11:45 am

Multi-Omic Integration in the Clinical Sciences

Discussion Leader: Irwin Kurland, Albert Einstein College of Medicine

Propionate Induces an Apparent Conflict Between Fluxomic and Metabolomic Measures in the Perfused Mouse Heart
Matthew Merritt, University of Florida

The Age Of Multi-Omics Has Arrived - Accelerating Integrated Perspectives In Biology
Devin Drew, Thermo Fisher Scientific

OneOmics™: Integrate Multi-Omics Data Seamlessly in the Cloud
Matthew Skaley, SCIEX

12:00 pm - 2:00 pm

Lunch: Vendor Spotlight & Poster Review

A Multi-Omics Study Elucidates an Increase in Bio-Production Efficiency
Gary Kruppa, Bruker

Lunch served in lobby as you mix and mingle with our vendors and poster authors

2:15 pm - 3:45 pm

Customers Meet Vendors

Introduction
Discussion Leader: Alla Kloss, Genzyme

Customer Panel
Darren Dumlao, Pfizer
Harvey Lieberman, Sanofi
David Pirman, Agios Pharmaceuticals

Vendor Panel
Mark Bennett, Waters Corporation
Ralf Bogumil, Biocrates
Suraj Dhungana, Waters Corporation
Faith Hays, Shimadzu Scientific Instruments
Ken Jones, SCIEX
Gary Kruppa, Bruker
Christine Miller, Agilent Technologies
Matthew Skaley, SCIEX
Amanda Souza, Thermo Fisher Scientific

4:00 pm - 5:00 pm

Graduate Student Workshop

Catalyzing Curiosity: Bridging Passion and Discovery

Curiosity is perceived to be an innate quality and essential characteristic of any scientist. The ideas, which flow from imagination into high-impact research, are seemingly natural; graduate school, and specifically doctoral education, is the ideal environment to cultivate this creativity and intuition. Our symposium on “Catalyzing Curiosity: Bridging Passion and Discovery” is intended to foster graduate students’ passions, which will eventually fuel their signature brand of science and lead to the generation of creative, novel scientific investigations. Fundamental discoveries arose from pure curiosity, a favorite being the discovery of buckminsterfullerene, or the “buckyball.” We are familiar with the results, but how did Drs. Curl, Heath, and Kroto distill their academic curiosity into a research project? Let's examine the relationships between initial questions, unexpected developments, and the growth of new curiosity-driven chemistry.

Mentors
Don Chace, Medolca Laboratories
Paul Corcoran, McKinley Scientific
Gabriele Cruciani, University of Perugia
Steve Fannin, Bruker Daltonics
Todd Gillespie, Eli Lilly & Company
Faith Hays, Shimadzu
David Heywood, Waters Corporation
Eugene Inman, Eli Lilly and Company (Ret)
John Janiszewski, Pfizer
Alla Kloss, Genzyme
Yutai Li, Merck
Carla Marshall-Waggett, New Objective
Nalini Sadagopan, Agilent Technologies
Martin Steel, McKinley Scientific
Jeremiah Tipton, BioTech & OMICSx Solutions, LLC
Baljit Ubhi, SCIEX
Roy Vaz, Sanofi
Richard Yost, University of Florida

5:15 pm

Closing Remarks

Tim Garrett, University of Florida